Endocrine Abstracts

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder that affects women of reproductive age. Clinical and biochemical characteristics are similar to metabolic syndrome. Insulin resistance in patients with metabolic syndrome, is associated with serum uric acid levels. In our study, we aimed to investigate the relationship between serum uric acid levels and clinical and laboratory in PCOS patients.Materials and Method: PCOS ...

Aim: The risk of cardiovascular mortality is high in patients with acromegaly. In this study, we intent to evaluate serum lipid profile in patients newly diagnosed with acromegaly and determine its association with increased growth hormone (gh) and insulin like growth factor-1 (igf-1) levels.Material and method: This study includes 57 patients newly diagnosed with acromegaly in our hospital (mean age 44.1±13.8 years; mean bmi 29.6±5.4 kg/m...

Familial hypocalciuric hypercalcemia is an inherited disease caused by inactivating heterozygous mutations in the gene encoding calcium-sensitive receptors, that affects calcium metabolism and generally follows a benign course. It must be also considered in the differential diagnosis of hyperparathyroidism. Six patients presenting to our internal diseases clinic between January, 2010, and June, 2015, were evaluated in terms of clinical and biochemical parameters. The youngest ...

Purpose: The purpose of this study was to evaluate the relation polycystic ovarian syndome (PCOS) and the thiol/disulfide balance, used as a marker of oxidative stress, by measuring that exchange using a novel technique.Material/methods: Fourty nine subjects diagnosed with PCOS and 44 healthy were included in the study. Thiol/disulfide homeostasis concentrations were measured by a newly developed method. After native thiol, total thiol and disulfide leve...

Insulinoma is generally a rare benign tumor of the pancreas islet cell. The typical clinical symptom of insulinoma are repetitive hypoglycemia attacks. Insulinoma with coexisting diabetes is extremely rare condition, We aim to present a case with insulinoma conmomittant with type 2 diabetes mellitus.Case report: A 65-year-old woman diagnosed with type 2 diabetes mellitus was admitted by our internal medicine clinic. She complained from perspiration and t...

Aim: Radioactive iodine (RAI) ablation therapy is used as part of the treatment for hyperthyroidism. Recently, low dose applied 131I treatment for hyperthyroidism has decreased the need for thyroidectomy. The aim of this study was to evaluate serum fasting glucose (FG) values in pre and post treatment RAI patients.Materials and Methods: Thirty-two patients with hyperthyroidism (mean age 56.0±14.5 years; range 24–83) treated with a si...

Introduction and objective: Recently, a lot of studies associated with high mean platelet level (MPV) in patients with hypo- and hyperthyroidism has reported in medical litherature. But it is not clear whether or not radioactive iodine treatment effect on platelet activity. It is well known that elevated platelet size is associated with its high enzymatic and metabolic activity. Aim of our preliminary study is to determine the platelet size via MPV level in hyperthyroid patien...

Introduction: Acromegaly is a chronic disorder characterized by chronic growth hormone (GH) excess. In most of cases, GH hypersecretion is derived from somatotroph cell tumors. Survivin is a member of apoptosis protein family, which was recently showed to be expressed in different benign and malignant human tumors. A number of studies showed overexpression of survivin in pituitary adenomas. This study is intended to determine circulating levels of survivin in patients with acr...

Aim: 402 patients who were admitted and FNA was done in the Endocrinology Clinic at EBEAH were enrolled in this study. 340 (85%) of them were females and 62 (15%) of them were males. The age range was between 16 and 82. There weren’t any statistical differences in age between both sexes. Thyroid cancer is reported to constitute <2% of cancers in humans. At the same time, it is the most lethal endocrine malignancy. In the literature it is stated that 3% of all cancers ...

Introduction and aim: Bethesda system for thyroid cytopathology has been widely used recently. Approximately 3–7% of thyroid fine-needle aspiration (FNA) biopsy is considered as malign. Suspicious or malign nodules should likely to be resected. Aim of this study is to confirm the diagnosis of malign or suspicious for malignity according to Bethesda classification in patients with nodular goitre after thyroidectomy.Materials and methods: Results of F...